Answer by Michaeldx · Dec 09, 2016 at 11:07 PM
I have seen this happen but I haven't figured out WHY it's happening yet.
For a work-around, launch Edge from UFT either from the 'Record>Record and Run Settings' menu or by right clicking the Agent Icon on the desktop and getting the "target" path and using SystemUtil.Run:
SystemUtil.Run "<target path>", "<url>"
It may be some security issue. If I find out, I will edit this post with the answer.