The HP official list of support MS Word and Excel version is listed in the UFT Product Availablity Matrix (PAM) which is release for each version of UFT. These can be found at [https://supportweb.orasi.com/SupportWeb/ProductDownloads.aspx](https://supportweb.orasi.com/SupportWeb/ProductDownloads.aspx) .
Looking at the UFT 12.5x PAM Excel and Word 2013 (Not for Automation) is last listed under supported. 2016 is not listed which indicates HPE has not tested these versions.
I have found post to HP and the ressponses can be found at:
Office 365
[http://community.hpe.com/t5/Unified-Functional-Testing-QTP/Office-365/m-p/6839851/thread-id/3660](http://community.hpe.com/t5/Unified-Functional-Testing-QTP/Office-365/m-p/6839851/thread-id/3660)
Excel/word 2016
[http://community.hpe.com/t5/Unified-Functional-Testing/Support-for-Word-Excel-and-Office-2016/m-p/6846222#M20356](http://community.hpe.com/t5/Unified-Functional-Testing/Support-for-Word-Excel-and-Office-2016/m-p/6846222#M20356)