I've done this before using the FileSystemObject in VBScript. You can read in text from basically any type of text file that could be read by Notepad in Windows. I'll give you some sample code to let you try this with in your test.
Basically, you will need to create a loop that continues reading lines from your text file until it reaches the end of file (the end of the text stream). You read the line in to a variable, and then we need to use the VBScript 'Split' operation to chop the string up using the commas as delimeters (separators). This will create a dynamic zero-based array that we can then use to populate the fields using the index number of the array value for input. You would need to make sure that there would be enough values for use as input in your application:
Set FSO = CreateObject(''Scripting.FileSystemObject'')
Set FS = FSO.OpenTextFile(''C:DataFilesMyData.txt'',1) 'open file for reading
Do While FS.AtEndOfStream <> True
MyLine = FS.ReadLine
MyArray = Split (MyLine, '','') 'split using the comma. Use whatever delimeter you wish here
'Use array values for input
Window(''Window'').WinEdit(''Field 1'').Set MyArray(0)
Window(''Window'').WinEdit(''Field 2'').Set MyArray(1)
Window(''Window'').WinEdit(''Field 3'').Set MyArray(0)
Window(''Window'').WinButton(''Submit'').Click
Window(''Window'').WinButton(''New'').Click
Loop ' Repeat until data runs out
'Cleanup
Set FS = Nothing
Set FSO = Nothing