In ALM 11 and 11.5 there was no support for a user that was on a Mac based computer, Starting with ALM 12 through ALM 12.21 Mac users can only access the defects and requirements through the new ''WEB'' client. The regular ALM client still uses .net in ALM 12-12.21 so it does not support the regular client being using in a MAC OS. The new version of ALM 12.50 DOES Not have support for Mac in any form or fashion.

See below link: https://hpln.hpe.com/product/alm/pages/3376

For native support utilizing the MAC OS there is no support other than the two versions mentioned above. However there are workarounds that are available to include VM hosting. remote access, and Boot Camp utilizing Windows OS (and this is due to the Active X components required that Microsoft owns and licenses and has yet to make available to other OS system, hence the reliance on IE so heavily).

If you are interested in some of the work arounds see the following post: http://eyeontesting.com/questions/2994/are-apple-products-compatible-to-use-with-hp-produ.html

Hope this helps as well,
Dan