Starting with UFT the internet options are ran when UFT is installed and not after installed. The permissions needed to be set during the install and during normal usage are describe in HP document [KM183747]. Also, the UFT Installation Guide > Chapter 2: Installing UFT >Installing UFT > UFT Configuration Has the following statement.
Configure Internet Explorer settings. Select this check box
to automatically configure the Internet Explorer options that
enable UFT to use the Microsoft Script Debugger application
during test runs.
You can also configure these options manually before
running UFT. In Internet Explorer, select Tools > Internet
Options > Advanced. Then select Disable script
debugging and Enable third-party browser extensions.