No , with TruClient you do not have to worry about installing a client agent when you perform your load test. However, you do need to ensure the following:

* The Load Generators are patched the same as the LoadRunner Controller / Vugen
* The Load Generators can access the application(s)manually
* Do notuse IE 11 as it is not compatiable with LoadRunner and Truclient at this time.
* After creating a script, it is a good practice to run concurrency test consisting 3 concurrent vusers executing the script. This will ensure they execute with out issues.