Hi HomerJ,
I have had heard of this and there is a KM article addressing it (KM03793246) and the recommendation is the following:
Locate the "ALM-Client.exe.config" file located in the path where the ALM client files are located, usually in the user's profile: C:Users<wiindows_user>AppDataLocalHPALM-Client<alm_version>
For example: C:Usersalex_almAppDataLocalHPALM-Client15.51.0.0_952
Open the file for editing
Locate the element "<runtime>" in the file
Within the "<runtime>" section add the line: <loadFromRemoteSources enabled="true"/>
It should look like this...
<runtime>
<startup useLegacyV2RuntimeActivationPolicy="true"> This is the highlighted line in the KM document
<assemblyBinding xmlns="urn:schemas-microsoft-com:asm.v1">
<probing privatePath="3rdParty"/>
<dependentAssembly>
Save changes and run the ALM Client Launcher Again
Hope this helps resolve your issue,
Dan