Yes. By default, the LoadRunner agent user is configured to spawn new processes (mdrv) to impersonate and run under the IUSR_METRO Windows account. If you change the Windows account for the LoadRunner agent user, it will still run under the System account, but it will impersonate the modified/reconfigured user.
For TruClient IE to run successfully, the Windows account used should have the following security group policies enabled:
* Act as part of the operating system: Required to log on as a user (authenticate like a user) and gain access to the same resources that the user is authorized to access.
* Replace a process level token: Allows a parent process to replace the access token that is associated with a child process.